Desirous of starting a family, the young Catholic housewife, Rosemary Woodhouse, and her struggling actor husband, Guy, move into the Bramford: New York's iconic building that brims with unpleasant stories of obscure dwellers and ghastly occurrences. Before long, the young couple is befriended by their somehow eccentric next-door neighbours, Roman and Minnie Castevet, and, shortly after, Rosemary gets pregnant. However, little by little--as the inexperienced mother becomes systematically cut off from her circle and friends--alarming hints of a sinister and well-planned conspiracy begin to emerge, enfolding timid Rosemary in a shroud of suspicion and mental agony. In the end, why is everyone so conveniently eager to help? Furthermore, why is Guy allowing it?